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Nahaufnahme mehrerer Probenröhrchen, die auf einem Tisch liegen. Im Hintergrund ist unscharf der Schriftzug "Charité" auf einem Formular erkennbar.

Feldmeier lab - Epidemiology and Control of Neglected Tropical Diseases (NTD)

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Group leader

Prof. Dr. Hermann Feldmeier

Group leader "Neglected Tropical Diseases"Charité – Universitätsmedizin Berlin

Postal address:Hindenburgdamm 3012203 Berlin

Lab Members

  • Madeleine Neveux
  • Niklas Weber

Projects

  • Elimination of Tungiasis (sand flea disease) in Napak District, Uganda. A community-based OneHealth Approach
  • Tungiasis in East Africa: an interdisciplinary approach to understand parasite-host-interactions. Together with Dr. Jürgen Krücken, FU Berlin
  • Diagnosis of female genital schistosomiasis through an AI based mobile App. Together with Dr. Angela Schuster, Charité University Medicine

Projects in planning

  • Morbidity and control of tungiasis in Amerindian populations in the Amazon Lowland
  • Development of morbidity in preschool-age children and their importance in the maintenance of the transmission cycle of S. haematobium in Madagascar

Key publications

Tungiasis

Abrha S, Christenson JK, McEwen J, Tesfaye W, Vaz Nery S, et al. (2021) Treatment of tungiasis using a tea tree oil-based gel formulation: protocol for a randomised controlled proof-of-principle trial. BMJ Open.11:e047380.

Miller H, Ocampo J, Ayala A, Trujillo J, Feldmeier H (2019) Very severe tungiasis in Amerindians in the Amazon lowland of Colombia: A case series. PLOS Neglected Tropical Diseases.13:e0007068.

Mutebi F, Krucken J, Feldmeier H, Waiswa C, Mencke N, et al. (2017) High intensity of Tunga penetrans infection causing severe disease among pigs in Busoga, South Eastern Uganda. BMC Veterinary Research.13:206.

Elson L, Wiese S, Feldmeier H, Fillinger U (2019) Prevalence, intensity and risk factors of tungiasis in Kilifi County, Kenya II: Results from a school-based observational study. PLoS Negl Trop Dis.13:e0007326.

Wiese S, Elson L, Feldmeier H (2018) Tungiasis-related life quality impairment in children living in rural Kenya. PLoS Negl Trop Dis.12:e0005939.

Wiese S, Elson L, Reichert F, Mambo B, Feldmeier H (2017) Prevalence, intensity and risk factors of tungiasis in Kilifi County, Kenya: I. Results from a community-based study. PloS Neglected Tropical Diseases.11:e0005925.

Nordin P, Thielecke M, Ngomi N, Mudanga GM, Krantz I, et al. (2017) Treatment of tungiasis with a two-component dimeticone: a comparison between moistening the whole foot and directly targeting the embedded sand fleas. Tropical Medicine and Health.45:e6.

Thielecke M, Nordin P, Ngomi N, Feldmeier H. Treatment of tungiasis with dimeticone: A proof-of-principle study in rural Kenya. PLoS Negl Trop Dis. 2014;8(7):e3058.

Thielecke M, Raharimanga V, Rogier C, Stauss-Grabo M, Richard V, Feldmeier H. Prevention of tungiasis and tungiasis-associated morbidity: A randomized, controlled field study in rural Madagascar. PLoS Negl Trop Dis. 2013;7(9):e2426.

Cutaneous larva migrans

Reichert F, Pilger D, Schuster A, Lesshafft H, Guedes de Oliveira S, et al. (2018) Epidemiology and morbidity of hookworm-related cutaneous larva migrans (HrCLM): Results of a cohort study over a period of six months in a resource-poor community in Manaus, Brazil. PLoS Negl Trop Dis.12:e0006662.

Reichert F, Pilger D, Schuster A, Lesshafft H, Guedes de Oliveira S, Ignatius R, et al. Prevalence and Risk Factors of Hookworm-Related Cutaneous Larva Migrans (HrCLM) in a Resource-Poor Community in Manaus, Brazil. PLoS Negl Trop Dis. 2016;10(3).

Shimogawara-Furushima R, Hata N, Schuster A, Lesshafft H, Guedes de Oliveira S, Akao N, et al. Hookworm-related cutaneous larva migrans in patients living in an endemic community in North Brazil: immunological patterns before and after ivermectin treatment. Eur J Microbiol Immunol. 2013;3(4):258-66.

Schuster A, Lesshaft H, Reichert F, Talhari S, Guedes de Oliveira S, Ignatius R, et al. Hookworm-related cutaneous larva migrans in North Brazil: Resolution of clinical pathology after a single dose of ivermectin. Clin Infect Dis. 2013;57(8):1155-7.

Schuster A, Lesshaft H, Reichert F, Ignatius H, Feldmeier H (2011) Life quality impairment caused by hookwork- related cutaneous larva migrans (HrCLM) in  resource-poor communities in Manaus, Brazil. PloS Neglected Tropical Diseases.5:e1355.

Scabies

Miller H, Trujillo-Trujillo J, Feldmeier H (2018) In Situ Diagnosis of Scabies Using a Handheld Digital Microscope in Resource-Poor Settings—A Proof-of-Principle Study in the Amazon Lowland of Colombia. Tropical Medicine and Infectious Disease.3:116.

Walter B, Heukelbach J, Fengler G, Worth C, Hengge U, Feldmeier H. Comparison of dermoscopy, skin scraping, and the adhesive tape test for the diagnosis of scabies in a resource-poor setting. Arch Dermatol. 2011;147(4):468-73.

Worth C, Heukelbach J, Fengler G, Walter B, Liesenfeld O, et al. (2010) Impaired life quality in adults and children with scabies from an impoverished community in Brazil. International Journal of Dermatology.51:275-82.

Feldmeier H, Jackson A, Ariza L, Calheiros CM, Soares Vde L, et al. (2009) The epidemiology of scabies in an impoverished community in rural Brazil: presence and severity of disease are associated with poor living conditions and illiteracy. J Am Acad Dermatol.60:436-43.

Jackson A, Heukelbach J, Feldmeier H (2007) Transmission of scabies in a rural community. Braz J Infect Dis.11:386-7.

Female Genital Schistosomiasis

Schuster A, Randrianasolo B, Rabozakandraina O, Ramarokoto CE, Brønnum D, et al. (2022 in press) Knowledge, experiences, and practices of women affected by female genital schistosomiasis in rural Madagascar Part I - Disease perception, health impairment and social impact. PloS Neglected Tropical Diseases.

Randrianasolo BS, Jourdan PM, Ravoniarimbinina P, Ramarokoto CE, Rakotomanana F, Ravaoalimalala VE, et al. Gynecological manifestations, histopathological findings, and schistosoma-specific polymerase chain reaction results among women with Schistosoma haematobium infection: a cross-sectional study in Madagascar. J Infect Dis. 2015:jiv035.